Cell and Image-Based Assays for the Functional Evaluation of Gene Therapies Targeting Muscle Disorders
Time: 8:30 am
day: Day 1
Details:
- Describing image-based bioassays suitable for measuring activity and functionality of gene therapy products targeting multiple muscle disorders, including DMD and DM1
- The MyoScreen Platform enhances the standardization of myotube culture compared to conventional culture plates, allowing for the reduction of inherent variability in cell-based assays, and high throughput imaging and analysis of specific proteins
- Described bioassays provide insights into the structure-function relationship of therapeutics and can be customized as potency assays, from early CMC development to lot release
