Designing Activity Assays for Non-Enzymatic/Structural Protein Products to Confidently & Robustly Measure Potency
Time: 9:00 am
day: Day 2
Details:
- Generating a release assay for measuring downstream protein effects to supplement binding assays and prove potency
- What kind of in vitro assays are acceptable? Assessing and clarifying agency expectations on binding assay data versus gene-knockdown versus true activity assays
- Establishing alternative assays to prove that binding studies are meaningful and indicative of potency
