Designing Activity Assays for Non-Enzymatic/Structural Protein Products to Confidently & Robustly Measure Potency

Time: 9:00 am
day: Day 2


  • Generating a release assay for measuring downstream protein effects to supplement binding assays and prove potency
  • What kind of in vitro assays are acceptable? Assessing and clarifying agency expectations on binding assay data versus gene-knockdown versus true activity assays
  • Establishing alternative assays to prove that binding studies are meaningful and indicative of potency