ROUNDTABLE: Selecting Appropriate Cell Lines During Potency Assay Development to Maintain Biological Relevance & Reflect Potency In Vivo
Time: 12:50 pm
day: Day 2
Details:
Roundtable discussions include a larger focus on group discussion. A moderator will introduce the session topic and attendees then split into groups to discuss a series of predetermined agenda points. At the end, all groups report back on their discussions, and findings are collated.
This roundtable will cover:
- Discussing the factors influencing the appropriate selection of transducible cell lines for batch testing
- Comparing the relative advantages and disadvantages of working with immortalized versus primary cell lines for potency testing
- Overcoming limitations associated with utilizing vectors with high specificities in their tropism
- Understanding the importance of measuring transduction efficiency on your selected cell line to determine biological relevance
